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姓名:徐璐
性别:女
籍贯:山东招远
E-Mail:xlmmm600@sina.com
F-职称/职务:教授
通讯地址:沈阳市沈河区文化路103号
邮政编码:110016
学习/工作经历:
本科、硕士和博士均毕业于沈阳药科大学,获药学学士学位、药剂学硕士学位和药剂学博士学位。1998年至今,于沈阳药科大学药学院物理化学教研室工作。2006.4-2007.4在日本名城大学药学部工作,2014.10-2015.10在美国普渡大学做访问学者。
兼职情况:
辽宁省细胞生物学学会医用高分子与细胞生物学专业委员会副主任委员
沈阳药科大学学报编委
科研/获奖情况:
主持及参与国家自然科学基金、科技部重大新药创制、中国博士后基金等国家、省市级科研项目20余项,授权发明专利3项,以第一作者或通讯作者发表SCI论文30余篇。主要研究方向为新型纳米递释系统及缓控释制剂的研究。获得辽宁省自然科学学术成果三等奖1项,沈阳市自然科学学术成果二等奖2项。
教学/指导研究生情况:
主讲本科物理化学,物理化学(留学生)课程,指导药剂学、化学专业硕士研究生,药剂学博士研究生。
发表论文/出版著作:
以第一作者或通讯作者发表SCI论文30余篇,代表性论文如下:
1. Construction of calcium carbonate-liposome dual-film coated mesoporous silica as a delayed drug release system for antitumor therapy, Colloids and Surfaces B: Biointerfaces, 2022, 212: 112357-112365. (IF=5.999)
2. Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery, Journal of Controlled Release, 2022, 342:1-13. (IF=11.467)
3. Alanine modified chiral-responsive mesoporous silica as nanocarriers for improved oral bioavailability of carvedilol, Microporous and Mesoporous Materials, 2021, 330:111634-111647. (IF=5.876)
4. Successively triggered Rod-shaped protocells for enhanced tumor
Chemo-Photothermal therapy, European Journal of Pharmaceutics and
Biopharmaceutics, 2021, 169:1-11. (IF=5.589)
5. Chiral mesoporous silica materials: a review on synthetic strategies and applications, Molecules, 2020, 25:1-21. (IF=4.412)
6. Preparation and application of mesoporous core-shell nanosilica using leucine derivative as template in effective drug delivery, Chinese Chemical Letters, 2020, 31: 1165-1167. (IF=6.779)
7. Evaluation of the solid dispersion system engineered from mesoporous silica and polymers for the poorly water soluble drug indomethacin: in vitro and in vivo, Pharmaceutics, 2020, 12: 144-162. (IF=6.321)
8. Preparation and dissolution characteristic evaluation of carvedilol-Kollicoat IR solid dispersions with HPMC and MC as combined carriers, Powder technology, 2020, 360:1220-1226. (IF=5.134)
9. Cancer cell membrane-camouflaged nanorods with endoplasmic reticulum targeting for improved antitumor therapy, ACS Applied Materials & Interfaces, 2019, 11(50): 46614-46625. (IF=8.758)
10. Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers, Nature Communications, 2018, 9(1): 2607-2618. (IF=11.878)
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