赵明

姓名：赵明

性别：女

籍贯：辽宁省阜新市

政治面貌：群众

联系邮箱：syphuzm@163.com

研究方向：智能响应型纳米递药系统用于肿瘤免疫治疗研究

职称：特聘副教授

学习/工作经历：2017年毕业于沈阳药科大学获药学学士学位，2020年毕业于沈阳药科大学获药剂学硕士学位，2023年毕业于沈阳药科大学获药剂学博士学位。2023年11月至今在沈阳药科大学药学院物理化学教研室工作。

科研成果：

科研项目

1.基于三元联动策略的生物正交纳米反应器用于上皮性卵巢癌治疗研究，辽宁省教育厅基本科研项目，基金编号LJ212410163025（负责人）

2.基于调控细胞焦亡与cGAS-STING通路的生物正交纳米反应器用于结肠癌治疗研究，辽宁省科技计划联合计划项目（自然科学基金-面上项目），基金编号2024-MSLH-436（负责人）

近年来发表代表性论文

(1)Ming Zhao^#; Ji Li^#; Fan Chen; Yanyan Han; Dawei Chen*; Haiyang Hu*; Engineering nanoparticles boost TNBC therapy by CD24 blockade and mitochondrial dynamics regulation, Journal of Controlled Release, 2023, 355: 211-227. (IF=10.5)

(2)Ming Zhao^#; Ji Li^#; Jingwen Liu; Moxi Xu; Hongrui Ji; Siwen Wu; Dawei Chen*; Haiyang Hu*; Charge-switchable nanoparticles enhance Cancer immunotherapy based on mitochondrial dynamic regulation and immunogenic cell death induction, Journal of Controlled Release, 2021, 335: 320-332. (IF=11.467)

(3)Zhenhua Li; Ziyue Xi; Chuanyong Fan; Xinran Xi; Yao Zhou; Ming Zhao*; Lu Xu*; Nanomaterials Evoke Pyroptosis Boosting Cancer Immunotherapy, Acta Pharmaceutica Sinica B, 2024. (IF=14.7)

(4)Yuyi Xu^#; Ming Zhao^#; Jinxue Cao; Ting Fang; Jian Zhang; Yanli Zhen; Fangli Wu; Xiaohui Yu; Yaming Liu; Ji Li*; Dongkai Wang*; Applications and recent advances in transdermal drug delivery systems for the treatment of rheumatoid arthritis, Acta Pharmaceutica Sinica B, 2023, 13: 4417-4441. (IF=14.7)

(5)Hongyu Yang^#; Ming Zhao^#; Dandan Xing; Jian Zhang; Ting Fang; Faxing Zhang; Zhihao Nie; Yaming Liu; Lihua Yang; Ji Li*; Dongkai Wang*; Contact lens as an emerging platform for ophthalmic drug delivery: A systematic review, Asian Journal of Pharmaceutical Science, 2023, 18: 100847. (IF=10.7)

(6)Jiaping Liu; Ziyue Xi; Chuanyong Fan; Yihua Mei; Jiale Zhao; Yingying Jiang; Ming Zhao*; Lu Xu*; Hydrogels for nucleic acid drugs delivery, Advanced Healthcare Materials, 2024, 2401895. (IF=10)

(7)Ming Zhao; Ji Li; Hongrui Ji; Dawei Chen; Haiyang Hu*; A versatile endosome acidity-induced sheddable gene delivery system: increased tumor targeting and enhanced transfection efficiency, International Journal of Nanomedicine, 2019, 14: 6519-6538. (IF=5.115)

(8)Ming Zhao; Ji Li; Dawei Chen; Haiyang Hu*; A Valid Bisphosphonate Modified Calcium Phosphate-Based Gene Delivery System: Increased Stability and Enhanced Transfection Efficiency In Vitro and In Vivo, Pharmaceutics, 2019, 11:468. (IF=4.421)

(9)Ji Li^#; Ming Zhao^#; Wendi Liang; Siwen Wu; Zheran Wang*; Dongkai Wang*; Codelivery of Shikonin and siTGF-β for enhanced triple negative breast cancer chemo-immunotherapy, Journal of Controlled Release, 2022, 342: 308-320. (IF=10.8)

(10)Chang Peng^#; Ming Zhao^#; Xuan Wang; Min Yan; Yanyan Han; Dawei Chen*; Haiyang Hu*; Manganese ion gradient liposomes modified by disulfide bond enhance cellular uptake and tumor immunity, Materials & Design, 2023, 233: 112178. (IF=7.6)

指导研究生情况：协助指导硕士研究生